Handbook of Experimental Pharmacology 201 - Drug Transporter ...

Martin F. Fromm, Richard B. Kim

• 19 november 2010
• 9783642145414

Samenvatting:

It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.