Welfare Aspects of Transgenic Animals

L. F. M. van Zutphen

• 20 maart 1997
• 9783540618393

Samenvatting:

New well-defined animal models, developed either by micro injection techniques or by homologous recombination in embryonic stem (ES) cells, have become widely available and several classical animal models have now been replaced by these transgenic models.

The quality of animal models used in biomedical research has increased substantially since the first successful microinjections of foreign DNA fragments into a mouse zygote in the early 1980s. New well-defined animal models developed either by microinjection techniques or by homologous recombination in embryonic stem (ES) cells, have become widely available and several classical animal models have now been replaced by these transgenic models. Transgenic animals also fulfill increasingly important roles in other fields, like livestock production or in biopharming. In the framework of the European Commission's Biotechnology Programme, a workshop has been organized at Utrecht University (30 October, 1995) with leading experts in the field of animal transgenesis and animal welfare as presenting authors. This book summarizes the papers presented at the workshop.

This text constitutes the proceedings of the EC Workshop on Welfare Aspects of Transgenic Animals held in October 1995. The techniques of transgenesis and some major fields of application as well as personal views on aspects of animal welfare are presented. The book also deals with general aspects of animal welfare and with ethical and legal aspects of producing or using transgenic animals.